Targeted silencing of GNAS in a human model of osteoprogenitor cells results in the deregulation of the osteogenic differentiation program

IntroductionThe dysregulation of cell fate toward osteoprecursor cells associated with most GNAS-based disorders may lead to episodic de novo extraskeletal or Camo Hides ectopic bone formation in subcutaneous tissues.The bony lesion distribution suggests the involvement of abnormal differentiation of mesenchymal stem cells (MSCs) and/or more commit

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Intracranial Ricocheting of Bullet from Anterior Clinoid Process

Gunshot Elbow Guards wounds to the head are usually mortal injuries.We present a unique case of intracranial ricocheting of bullet without neurological deficits.Patient was treated conservatively with antibiotics for one week and prophylactic anticonvulsants for six weeks.Patient is doing well at six months follow up.Repeat X-ray skull showed that

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